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CS-W001157 4
Total: USD 88.00

3-Hydroxyquinoline

  • CAS No. 580-18-7

  • Cat. No. CS-W008203
  • Purity≥96%
  • MDL No.MFCD00169018

*For research and further manufacturing use only, not for direct human use.

3-Hydroxyquinoline|CS-W008203

Structure of 580-18-7

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General Information

  • CAS No. 580-18-7
  • Cat. No. CS-W008203
  • Purity ≥96%
  • MDL No. MFCD00169018
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇NO
  • Molecular Weight 145.16
  • Synonym(s) None
  • SMILES C1=C2C(=NC=C1O)C=CC=C2

Description

3-Hydroxyquinoline is a heterocyclic compound featuring a hydroxyl group at the 3-position of the quinoline scaffold. This structural motif imparts enhanced solubility and reactivity, enabling direct incorporation into metal-chelating ligands, fluorescent probes, and pharmaceutical intermediates. The phenolic functionality supports hydrogen bonding and facilitates derivatization under mild conditions.

Application

3-Hydroxyquinoline serves as a versatile heterocyclic building block in medicinal chemistry and synthetic organic chemistry. Its hydroxyl group enables facile derivatization via etherification, esterification, or metal-catalyzed coupling reactions. The scaffold exhibits good bench stability and functional group tolerance, facilitating its use in constructing complex quinoline-based APIs and fluorescent probes.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   1.9404
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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