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CS-W001157 4
Total: USD 88.00

Uridine

  • CAS No. 58-96-8

  • Cat. No. CS-5153
  • Purity≥98%
  • MDL No.MFCD00006526

*For research and further manufacturing use only, not for direct human use.

Uridine|CS-5153

Structure of 58-96-8

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General Information

  • CAS No. 58-96-8
  • Cat. No. CS-5153
  • Purity ≥98%
  • MDL No. MFCD00006526
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂N₂O₆
  • Molecular Weight 244.20
  • Synonym(s) β-Uridine
  • SMILES O[C@H]1[C@@H](O)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1CO

Description

Uridine (CAS 58-96-8) integrates into RNA synthesis pathways, stabilizing nucleic acid precursors and modulating intracellular pyrimidine pools during metabolic labeling studies.

Application

Uridine (CAS 58-96-8) supports primary hippocampal neuron culture by enhancing survival and synaptic maturation in specialized medium formulations. It rescues metabolic deficits in mouse embryonic fibroblasts and human breast cancer cells under stress. Researchers deploy this nucleoside in chase sequencing to track RNA dynamics with high precision.

Synthesis

  • Route1

    References

    • Golden, Kathryn C.; Gregg, Brian T.; Quinn, John F. Tetrahedron Letters, 2010 , vol. 51, # 31 p. 4010 - 4013
  • Route2
    • 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-((trityloxy)methyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione|CS-0454578
      6554-10-5
    • ~95%
    • In-stock
      Uridine|CS-5153
      58-96-8

    References

    • Hwu, Jih Ru; Jain, Moti L.; Tsai, Fu-Yuan; Tsay, Shwu-Chen; Balakumar, Arumugham; Hakimelahi, Gholam H. Journal of Organic Chemistry, 2000 , vol. 65, # 17 p. 5077 - 5088
  • Route3

    References

    • Meier, Lidiane; Monteiro, Gustavo C.; Baldissera, Rodrigo A.M.; Sa, Marcus Mandolesi Journal of the Brazilian Chemical Society, 2010 , vol. 21, # 5 p. 859 - 866

Safety Information

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GHS Pictogram : N/A
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UN#: N/A
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Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   124.78
  • LogP   -2.8519
  • H_Acceptors   7
  • H_Donors   4
  • Rotatable_Bonds   2

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