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CS-W001157 4
Total: USD 88.00

Liquiritigenin

  • CAS No. 578-86-9

  • Cat. No. CS-6977
  • Purity≥98%
  • MDL No.MFCD00287289

*For research and further manufacturing use only, not for direct human use.

Liquiritigenin|CS-6977

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General Information

  • CAS No. 578-86-9
  • Cat. No. CS-6977
  • Purity ≥98%
  • MDL No. MFCD00287289
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₂O₄
  • Molecular Weight 256.25
  • Synonym(s) 4',7-Dihydroxyflavanone
  • SMILES O=C1C[C@@H](C2=CC=C(O)C=C2)OC3=CC(O)=CC=C13

Description

Isolated from Glycyrrhizae radix, Liquiritigenin (CAS 578-86-9) binds estrogen receptor alpha with moderate affinity and modulates NF-κB signaling in inflammatory cell models.

Application

Liquiritigenin (CAS 578-86-9) inhibits tumor metastasis in colorectal cancer models by targeting key invasion pathways and modulating epithelial-mesenchymal transition markers. It serves as a critical reference standard for UPLC analysis of Chaihu-Shugan-San extract. Researchers explore its antiviral potential against hepatitis C virus, leveraging its bioactive profile to disrupt viral replication cycles.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   66.76
  • LogP   2.8043
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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