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CS-W001157 4
Total: USD 88.00

4-Hydroxy-2-methylbenzoic acid

  • CAS No. 578-39-2

  • Cat. No. CS-W016305
  • Purity≥96%
  • MDL No.MFCD02182261

*For research and further manufacturing use only, not for direct human use.

4-Hydroxy-2-methylbenzoic acid|CS-W016305

Structure of 578-39-2

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General Information

  • CAS No. 578-39-2
  • Cat. No. CS-W016305
  • Purity ≥96%
  • MDL No. MFCD02182261
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈O₃
  • Molecular Weight 152.15
  • Synonym(s) 4-Hydroxy-o-toluic Acid
  • SMILES O=C(O)C1=CC=C(O)C=C1C

Description

4-Hydroxy-2-methylbenzoic acid features a phenolic hydroxyl group ortho to a carboxylic acid, enabling dual functionality in synthetic transformations. The methyl substituent enhances electron density at the aromatic ring, supporting selective derivatization under mild conditions. This compound serves as a key scaffold for bioactive molecule synthesis and functional materials development.

Application

4-Hydroxy-2-methylbenzoic acid serves as a versatile building block in synthetic organic chemistry, enabling the construction of substituted benzoic acid derivatives and heterocyclic scaffolds. Its ortho-methyl and para-hydroxyl groups provide distinct sites for selective functionalization, while the carboxylic acid moiety facilitates coupling reactions and salt formation. The compound exhibits good bench stability and is readily purified by recrystallization, supporting its use in medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H318
Precautionary Statements : P264-P270-P280-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   1.39882
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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