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CS-W001157 4
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4-(Dibutylamino)-2-hydroxybenzaldehyde

  • CAS No. 57771-09-2

  • Cat. No. CS-0453749
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-(Dibutylamino)-2-hydroxybenzaldehyde|CS-0453749

Structure of 57771-09-2

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General Information

  • CAS No. 57771-09-2
  • Cat. No. CS-0453749
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₂₃NO₂
  • Molecular Weight 249.35
  • Synonym(s) 4-(Dibutylamino)salicylaldehyde
  • SMILES CCCCN(CCCC)C1=CC(=C(C=C1)C=O)O

Description

4-(Dibutylamino)-2-hydroxybenzaldehyde features a hydroxyl group ortho to the aldehyde, enabling chelation and enhancing metal-binding affinity. The dibutylamino substituent imparts strong electron-donating character, increasing nucleophilicity at the aromatic ring. This combination enables use in coordination chemistry and as a ligand precursor under standard bench conditions.

Application

4-(Dibutylamino)-2-hydroxybenzaldehyde serves as a versatile building block in synthetic organic chemistry, enabling the construction of biologically relevant heterocycles and functionalized aromatic scaffolds. The ortho-hydroxy and aldehyde functionalities facilitate efficient condensation reactions, while the dibutylamino group provides moderate electron-donating character and enhanced solubility. Its bench-stable nature and compatibility with standard purification methods make it suitable for iterative synthesis workflows in medicinal chemistry and materials development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Computational Chemistry Data

  • TPSA   40.54
  • LogP   3.6113
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   8

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