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Structure of 57573-59-8
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6-Bromo-3-methylquinazolin-4(3H)-one features a brominated quinazolinone core with a methyl group at the 3-position, offering a reactive handle for cross-coupling and a stable scaffold for medicinal chemistry. This bench-stable compound integrates readily into target-directed libraries, enabling efficient access to bioactive heterocycles under standard conditions.
6-Bromo-3-methylquinazolin-4(3H)-one serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C6 position via palladium-catalyzed cross-coupling reactions. Its stability under standard reaction conditions and compatibility with diverse functional groups facilitate efficient synthesis of quinazoline-based scaffolds relevant to kinase inhibitor development. The methyl group at C3 enhances metabolic stability, while the 4(3H)-one tautomer provides a robust platform for further derivatization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: