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CS-W001157 4
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1-(1-Ethoxyethyl)-4-iodo-1H-pyrazole

  • CAS No. 575452-22-1

  • Cat. No. CS-D0585
  • Purity≥97%
  • MDL No.MFCD22123601
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-(1-Ethoxyethyl)-4-iodo-1H-pyrazole|CS-D0585

Structure of 575452-22-1

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Description

1-(1-Ethoxyethyl)-4-iodo-1H-pyrazole features a pyrazole core functionalized with an electron-deficient iodine at C4 and a bench-stable ethoxyethyl group at N1, enabling direct incorporation into cross-coupling reactions. The pendant alkoxy substituent enhances solubility in organic media while maintaining stability under standard handling conditions.

Application

1-(1-Ethoxyethyl)-4-iodo-1H-pyrazole serves as a versatile building block for constructing substituted pyrazole scaffolds in medicinal chemistry. The iodine moiety enables reliable cross-coupling reactions, while the 1-(1-ethoxyethyl) group provides stability and facilitates purification. Its bench-stable nature and compatibility with standard transition-metal-catalyzed transformations make it well-suited for iterative synthesis workflows in API development.

General Information

  • CAS No. 575452-22-1
  • Cat. No. CS-D0585
  • Purity ≥97%
  • MDL No. MFCD22123601
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁IN₂O
  • Molecular Weight 266.08
  • Synonym(s) 1-(1-Ethoxyethyl)-4-iodopyrazole
  • SMILES CCOC(N1C=C(C=N1)I)C

Computational Chemistry Data

  • TPSA   27.05
  • LogP   2.0427
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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