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CS-W001157 4
Total: USD 88.00

2-(2,4,6-Trichlorophenoxy)acetic acid

  • CAS No. 575-89-3

  • Cat. No. CS-0157713
  • Purity≥98%
  • MDL No.MFCD00053498

*For research and further manufacturing use only, not for direct human use.

2-(2,4,6-Trichlorophenoxy)acetic acid|CS-0157713

Structure of 575-89-3

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General Information

  • CAS No. 575-89-3
  • Cat. No. CS-0157713
  • Purity ≥98%
  • MDL No. MFCD00053498
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅Cl₃O₃
  • Molecular Weight None
  • Synonym(s) 2,4,6-Trichlorophenoxyacetic acid
  • SMILES C1=C(C=C(C(=C1Cl)OCC(=O)O)Cl)Cl

Description

This chlorinated phenoxyacetic acid features a trichlorophenyl ring system that confers enhanced lipophilicity and metabolic stability. The carboxylic acid group enables direct conjugation or salt formation, facilitating integration into agrochemical formulations. Designed for robust environmental persistence and plant growth regulation, it serves as a key intermediate in herbicide synthesis under standard bench conditions.

Application

2-(2,4,6-Trichlorophenoxy)acetic acid serves as a well-established auxin-type herbicide scaffold, enabling efficient synthesis of phenoxyalkanoic acid derivatives via standard esterification and amidation protocols. Its trichlorophenoxy group provides enhanced lipophilicity and metabolic stability, facilitating use in agrochemical development. The compound exhibits bench-stable handling, tolerates diverse functional groups, and functions reliably in coupling reactions for targeted pesticide and crop protection research.

Synthesis

  • Route1
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    • In-stock
      2-(2,4,6-Trichlorophenoxy)acetic acid|CS-0157713
      575-89-3

    References

    • Journal of the Indian Chemical Society, , vol. 68, # 3 p. 163 - 165
  • Route2
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      79-08-3
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      88-06-2
    • ~%
    • In-stock
      2-(2,4,6-Trichlorophenoxy)acetic acid|CS-0157713
      575-89-3

    References

    • Journal of Medicinal Chemistry, , vol. 27, # 8 p. 967 - 978
  • Route3

    References

    • Roczniki Chemii, , vol. 30, p. 633 Chem.Abstr., , p. 658

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P264-P270-P280-P301+P310-P305+P351+P338-P330-P337+P313-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   3.1102
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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