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CS-W001157 4
Total: USD 88.00

7-Methoxy-4-(trifluoromethyl)coumarin

  • CAS No. 575-04-2

  • Cat. No. CS-0071797
  • Purity≥98%
  • MDL No.MFCD00132980

*For research and further manufacturing use only, not for direct human use.

7-Methoxy-4-(trifluoromethyl)coumarin|CS-0071797

Structure of 575-04-2

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General Information

  • CAS No. 575-04-2
  • Cat. No. CS-0071797
  • Purity ≥98%
  • MDL No. MFCD00132980
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₇F₃O₃
  • Molecular Weight 244.17
  • Synonym(s) MFC
  • SMILES O=C1OC2=CC(OC)=CC=C2C(C(F)(F)F)=C1

Application

7-Methoxy-4-(trifluoromethyl)coumarin (CAS 575-04-2) serves as a sensitive fluorescent substrate in cytochrome P450 2E1 activity assays, enabling real-time monitoring of metabolic turnover. It also functions effectively in aromatase screening. Researchers leverage this dual-purpose reactivity to profile enzyme kinetics and assess inhibitor potency across xenobiotic metabolism pathways.

Synthesis

  • Route1
    • In-stock
      3-Methoxyphenol|CS-D1677
      150-19-6
    • null|null
      372-31-6
    • ~63%
    • In-stock
      7-Methoxy-4-(trifluoromethyl)coumarin|CS-0071797
      575-04-2

    References

    • Katkevics; Kontijevskis; Mutule; Suna Chemistry of Heterocyclic Compounds, 2007 , vol. 43, # 2 p. 151 - 159
  • Route2
    • null|null
      108-46-3
    • ~%
    • In-stock
      7-Methoxy-4-(trifluoromethyl)coumarin|CS-0071797
      575-04-2

    References

    • Journal of the Chemical Society, , p. 3235,3238
  • Route3

    References

    • Journal of the Chemical Society, , p. 3235,3238

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   39.44
  • LogP   2.8204
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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