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CS-W001157 4
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2-(2-Methyl-1,3-dioxolan-2-yl)acetic acid

  • CAS No. 5735-97-7

  • Cat. No. CS-0060072
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(2-Methyl-1,3-dioxolan-2-yl)acetic acid|CS-0060072

Structure of 5735-97-7

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General Information

  • CAS No. 5735-97-7
  • Cat. No. CS-0060072
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀O₄
  • Molecular Weight 146.14
  • Synonym(s) 2-(2-Methyl-1.3-dioxolan-2-yl)acetic acid
  • SMILES C1(CC(=O)O)(OCCO1)C

Description

This acetic acid derivative features a 2-methyl-1,3-dioxolan-2-yl group that confers enhanced stability and solubility in polar solvents. The protected aldehyde functionality enables controlled release in synthetic sequences. This compound integrates readily into complex molecular architectures under mild conditions.

Application

2-(2-Methyl-1,3-dioxolan-2-yl)acetic acid serves as a stable, bench-ready synthon for the introduction of α-hydroxyalkyl carboxylic acid motifs. Its dioxolane-protected aldehyde functionality enables selective transformations under mild conditions, facilitating efficient access to β-hydroxy acids and related building blocks via nucleophilic addition or reduction protocols. The molecule exhibits excellent functional group tolerance and simplifies purification in multi-step sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   55.76
  • LogP   0.2241
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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