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CS-W001157 4
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4-(4-AMinophenyl)benzoicacid

  • CAS No. 5730-78-9

  • Cat. No. CS-0132134
  • Purity≥98%
  • MDL No.MFCD01138446

*For research and further manufacturing use only, not for direct human use.

4-(4-AMinophenyl)benzoicacid|CS-0132134

Structure of 5730-78-9

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General Information

  • CAS No. 5730-78-9
  • Cat. No. CS-0132134
  • Purity ≥98%
  • MDL No. MFCD01138446
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₁NO₂
  • Molecular Weight 213.24
  • Synonym(s) None
  • SMILES O=C(O)C1=CC=C(C=C1)C=2C=CC(N)=CC2

Description

4-(4-Aminophenyl)benzoic acid features a conjugated aryl-aryl linkage with an electron-rich amine and a carboxylic acid functional group, enabling direct integration into bioconjugation workflows. This dual-functional scaffold supports efficient coupling in peptide synthesis and polymer derivatization under standard conditions.

Application

4-(4-Aminophenyl)benzoic acid serves as a versatile building block for conjugated aromatic systems, enabling efficient access to biaryl scaffolds via standard coupling reactions. Its dual functionality—readily derivatized amine and carboxylic acid groups—facilitates orthogonal transformations in medicinal chemistry and materials science. The compound exhibits good bench stability and is compatible with common purification methods, making it well-suited for iterative synthesis workflows.

Synthesis

  • Route1

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 17 p. 2395 - 2398
  • Route2

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 17 p. 2395 - 2398
  • Route3
    • null|null
      135-69-3
    • ~%
    • In-stock
      4-(4-AMinophenyl)benzoicacid|CS-0132134
      5730-78-9

    References

    • Journal of the American Chemical Society, , vol. 73, p. 2479,2480

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   2.634
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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