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CS-W001157 4
Total: USD 88.00

1,4-Epoxy-1,4-dihydronaphthalene

  • CAS No. 573-57-9

  • Cat. No. CS-W016390
  • Purity≥95%
  • MDL No.MFCD00167584

*For research and further manufacturing use only, not for direct human use.

1,4-Epoxy-1,4-dihydronaphthalene|CS-W016390

Structure of 573-57-9

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General Information

  • CAS No. 573-57-9
  • Cat. No. CS-W016390
  • Purity ≥95%
  • MDL No. MFCD00167584
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₈O
  • Molecular Weight 144.17
  • Synonym(s) 1,4-Dihydro-1,4-epoxynaphthalene
  • SMILES C1(O2)C=CC2C3=C1C=CC=C3

Description

3,4,5-trihydroxybenzaldehyde from Geum japonicum has dual inhibitory effect on matrix metalloproteinase 9; inhibition of gelatinoytic activity as well as MMP-9 expression in TNF-α induced HASMC.

Synthesis

  • Route1

    References

    • Uchiyama, Masanobu; Kobayashi, Yuri; Furuyama, Taniyuki; Nakamura, Shinji; Kajihara, Yumiko; Miyoshi, Tomoko; Sakamoto, Takao; Kondo, Yoshinori; Morokuma, Keiji Journal of the American Chemical Society, 2008 , vol. 130, # 2 p. 472 - 480
  • Route2
    • null|null
      110-00-9
    • null|null
      1373397-21-7
    • ~57%
    • 1,4-Epoxy-1,4-dihydronaphthalene|CS-W016390
      573-57-9

    References

    • Kovacs, Szabolcs; Csincsi, Adam I.; Nagy, Tibor Zs.; Boros, Sandor; Timari, Geza; Novak, Zoltan Organic Letters, 2012 , vol. 14, # 8 p. 2022 - 2025
  • Route3
    • null|null
      110-00-9
    • null|null
      583-53-9
    • ~12%
    • 1,4-Epoxy-1,4-dihydronaphthalene|CS-W016390
      573-57-9

    References

    • Sato, Hiroki; Isono, Naohiro; Miyoshi, Irie; Mori, Miwako Tetrahedron, 1996 , vol. 52, # 24 p. 8143 - 8158

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P233-P260-P261-P264-P271-P280-P302+P352-P304+P340-P362

Quality Control

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   2.3688
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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