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CS-W001157 4
Total: USD 88.00

Felbinac

  • CAS No. 5728-52-9

  • Cat. No. CS-8026
  • Purity≥98%
  • MDL No.MFCD00004351

*For research and further manufacturing use only, not for direct human use.

Felbinac|CS-8026

Structure of 5728-52-9

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General Information

  • CAS No. 5728-52-9
  • Cat. No. CS-8026
  • Purity ≥98%
  • MDL No. MFCD00004351
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₂O₂
  • Molecular Weight None
  • Synonym(s) 4-Biphenylacetic acid
  • SMILES O=C(O)CC1=CC=C(C2=CC=CC=C2)C=C1

Description

4-Biphenylacetic acid is a potential non-steroidal antiinflammatory agent and forms solid inclusion complex with -cyclodextrin. 4-Biphenylacetic acid on interaction with quinolone antibacterial agents induces functional blockade of the -aminobutyric acid receptors.4-Biphenylacetic acid was used in the synthesis of gastrosparing non-steroidal antiinflammatory drug.

Application

Felbinac serves as a well-established nonsteroidal anti-inflammatory drug (NSAID) scaffold, enabling targeted cyclooxygenase inhibition through its arylacetic acid core. Its stability and functional group tolerance facilitate direct incorporation into medicinal chemistry campaigns, while the phenyl substituent supports diverse derivatization for structure-activity relationship studies. The compound functions effectively in both academic and industrial synthesis workflows, offering predictable reactivity and reliable bench performance.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H319-H335
Precautionary Statements : P302+P352-P304+P340-P330

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.9807
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   3

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