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Structure of 57252-83-2
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3-Methylcyclobutanecarboxylic acid features a strained cyclobutane ring with a methyl substituent that modulates reactivity and steric profile. This structural motif delivers enhanced rigidity and controlled functionalization potential, enabling efficient incorporation into bioactive scaffolds and synthetic intermediates under standard conditions.
3-Methylcyclobutanecarboxylic acid serves as a valuable scaffold in medicinal chemistry and synthetic organic research, offering a rigid, substituted cyclobutane core with defined stereochemistry. Its carboxylic acid functionality enables straightforward derivatization via amide, ester, or acyl chloride formation, while the methyl substituent provides steric modulation and enhanced metabolic stability. The compound exhibits good bench stability and is compatible with standard coupling reactions, facilitating integration into complex molecular architectures such as bioactive heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3265
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: