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Structure of 57120-58-8
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2-Bromo-N-(tert-butyl)acetamide features a bromine-substituted alkyl chain attached to a sterically shielded amide nitrogen, enabling selective functionalization in complex synthesis. The tert-butyl group imparts enhanced stability and reduced nucleophilicity, while the electrophilic bromide facilitates cross-coupling reactions under mild conditions. This reagent serves as a key building block for bioactive molecule construction.
2-Bromo-N-(tert-butyl)acetamide serves as a versatile acylating agent and electrophilic bromide source in synthetic organic chemistry. Its tert-butyl group enhances bench stability and facilitates purification, while the bromoacetyl moiety enables efficient amide bond formation, nucleophilic substitution, and incorporation into heterocyclic scaffolds. Functions reliably in standard peptide coupling and conjugation workflows with broad functional group tolerance.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: