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CS-W001157 4
Total: USD 88.00

(2R)-3-Chloro-1,2-propanediol

  • CAS No. 57090-45-6

  • Cat. No. CS-W018500
  • Purity≥96%
  • MDL No.MFCD00135169

*For research and further manufacturing use only, not for direct human use.

(2R)-3-Chloro-1,2-propanediol|CS-W018500

Structure of 57090-45-6

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General Information

  • CAS No. 57090-45-6
  • Cat. No. CS-W018500
  • Purity ≥96%
  • MDL No. MFCD00135169
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₇ClO₂
  • Molecular Weight 110.54
  • Synonym(s) (R)-(-)-3-Chloro-1,2-propanediol; (R)-Monochlorohydrin; (R)-α-Chlorohydrin
  • SMILES OC[C@@H](O)CCl

Description

(2R)-3-Chloro-1,2-propanediol is a chiral diol featuring a chlorine substituent at the C3 position, offering enhanced reactivity in stereoselective transformations. This bench-stable compound integrates readily into synthetic sequences requiring defined stereochemistry and polar functionality.

Synthesis

  • Route1
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      24423-98-1
    • ~%
    • In-stock
      (2R)-3-Chloro-1,2-propanediol|CS-W018500
      57090-45-6

    References

    • EP1422213 A1, ; Page 18 ;
  • Route2
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      106-89-8
    • ~0%
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      51594-55-9
    • In-stock
      (2R)-3-Chloro-1,2-propanediol|CS-W018500
      57090-45-6
    • In-stock
      (S)-3-Chloropropane-1,2-diol|CS-W011275
      60827-45-4

    References

    • Schaus, Scott E.; Brandes, Bridget D.; Larrow, Jay F.; Tokunaga, Makoto; Hansen, Karl B.; Gould, Alexandra E.; Furrow, Michael E.; Jacobsen, Eric N. Journal of the American Chemical Society, 2002 , vol. 124, # 7 p. 1307 - 1315
  • Route3
    • null|null
      24423-98-1
    • ~%
    • In-stock
      (2R)-3-Chloro-1,2-propanediol|CS-W018500
      57090-45-6
    • In-stock
      (S)-3-Chloropropane-1,2-diol|CS-W011275
      60827-45-4

    References

    • EP1422213 A1, ; Page 13 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06,GHS08
Signal Word : Danger
UN#: 2689
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H290-H301-H315-H318-H330-H351-H360-H370-H372
Precautionary Statements : P234-P260-P264-P270-P271-P280-P284-P302+P352-P304+P340-P330-P362+P364-P390-P405-P406-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   -0.4216
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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