Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2,4,6-Trimethoxybenzoic acid

  • CAS No. 570-02-5

  • Cat. No. CS-W021498
  • Purity≥98%
  • MDL No.MFCD00016497

*For research and further manufacturing use only, not for direct human use.

2,4,6-Trimethoxybenzoic acid|CS-W021498

Structure of 570-02-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 570-02-5
  • Cat. No. CS-W021498
  • Purity ≥98%
  • MDL No. MFCD00016497
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂O₅
  • Molecular Weight 212.20
  • Synonym(s) Benzoic acid, 2,4,6-trimethoxy-
  • SMILES O=C(O)C1=C(OC)C=C(OC)C=C1OC

Description

This trimethoxybenzoic acid features three methoxy groups positioned at the 2, 4, and 6 ring locations, creating a highly electron-rich aromatic core. The carboxylic acid functionality enables direct coupling in amide bond formation, while the ortho-methoxy substituents provide steric shielding and enhanced solubility in organic solvents. This combination supports reliable derivatization under standard conditions without requiring protective group manipulation.

Application

2,4,6-Trimethoxybenzoic acid serves as a versatile building block in medicinal chemistry and agrochemical synthesis, offering enhanced solubility and metabolic stability through its three methoxy substituents. The carboxylic acid functionality enables straightforward derivatization via esterification, amidation, or coupling reactions, while the ortho-methoxy groups provide steric and electronic modulation. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for high-throughput screening campaigns and multi-step syntheses.

Synthesis

  • Route1

    References

    • Mannam, Sreedevi; Sekar Tetrahedron Letters, 2008 , vol. 49, # 6 p. 1083 - 1086
  • Route2

    References

    • Das, Rima; Chakraborty, Debashis Applied Organometallic Chemistry, 2011 , vol. 25, # 6 p. 437 - 442
  • Route3

    References

    • US6057315 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   64.99
  • LogP   1.4106
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   4

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2,4,6-Trimethoxybenzoic acid sigma2,4,6-Trimethoxybenzoic acid manufacturer2,4,6-Trimethoxybenzoic acid price2,4,6-Trimethoxybenzoic acid structure2,4,6-Trimethoxybenzoic acid SDSbuy 2,4,6-Trimethoxybenzoic acid2,4,6-Trimethoxybenzoic acid supplier2,4,6-Trimethoxybenzoic acid uses2,4,6-Trimethoxybenzoic acid molecular weightprice of 2,4,6-Trimethoxybenzoic acid2,4,6-Trimethoxybenzoic acid chemical name formula of 2,4,6-Trimethoxybenzoic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label