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Structure of 5689-18-9
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2-Cyclopropyl-2-phenylacetic acid features a sterically hindered benzylic carbon bearing both cyclopropyl and phenyl substituents, enhancing its metabolic stability. This structural motif enables robust integration into bioactive scaffolds, particularly in CNS-targeted pharmaceuticals and kinase inhibitors, where lipophilicity and conformational rigidity are critical.
2-Cyclopropyl-2-phenylacetic acid serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through established functional group transformations. Its rigid, sterically defined structure facilitates controlled stereochemistry in downstream applications. The molecule exhibits good bench stability and is compatible with standard coupling protocols, making it suitable for use in peptide conjugation and heterocycle construction.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: