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CS-W001157 4
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3-(Trimethylsilyl)propanoic acid

  • CAS No. 5683-30-7

  • Cat. No. CS-0698434
  • Molecule weight146.26
  • Purity≥98%
  • MDL No.MFCD00002761

*For research and further manufacturing use only, not for direct human use.

3-(Trimethylsilyl)propanoic acid|CS-0698434

Structure of 5683-30-7

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General Information

  • CAS No. 5683-30-7
  • Cat. No. CS-0698434
  • Purity ≥98%
  • MDL No. MFCD00002761
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₄O₂Si
  • Molecular Weight 146.26
  • Synonym(s) None
  • SMILES C[Si](C)(C)CCC(O)=O

Description

3-(Trimethylsilyl)propanoic acid features a silyl-protected carboxylic acid group, enabling stable storage and selective deprotection under mild conditions. This functional handle facilitates conjugation in synthetic biology workflows and serves as a robust building block for bioconjugation, polymer modification, and derivatization of biomolecules.

Application

3-(Trimethylsilyl)propanoic acid serves as a versatile silyl-protected carboxylic acid building block, enabling reliable functional group manipulation in synthetic workflows. Its trimethylsilyl group provides enhanced stability and facilitates selective deprotection under mild conditions, while the pendant carboxylic acid enables direct coupling reactions or further derivatization. This compound functions effectively in peptide synthesis, heterocycle construction, and the preparation of silicon-containing pharmaceutical intermediates, offering predictable reactivity and ease of purification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.7993
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   3

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