Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Bromo-2-methyl-1,3-benzoxazole

  • CAS No. 5676-56-2

  • Cat. No. CS-W005533
  • Purity≥95%
  • MDL No.MFCD08702771

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-methyl-1,3-benzoxazole|CS-W005533

Structure of 5676-56-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 5676-56-2
  • Cat. No. CS-W005533
  • Purity ≥95%
  • MDL No. MFCD08702771
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆BrNO
  • Molecular Weight 212.05
  • Synonym(s) 5-BroMo-2-Methylbenzoxazole
  • SMILES CC1=NC2=CC(Br)=CC=C2O1

Description

5-Bromo-2-methyl-1,3-benzoxazole is a heterocyclic compound featuring a bromine substituent at the 5-position and a methyl group at the 2-position on the benzoxazole core. This electron-deficient scaffold integrates readily into cross-coupling reactions, serving as a robust building block for pharmaceutical intermediates and functional materials. The molecule exhibits enhanced stability under standard handling conditions.

Application

5-Bromo-2-methyl-1,3-benzoxazole serves as a versatile building block in medicinal chemistry and heterocyclic synthesis. The bromine substituent enables palladium-catalyzed cross-coupling reactions, while the methyl group enhances metabolic stability and modulates electronic properties. Its bench-stable nature and compatibility with diverse functional groups facilitate efficient incorporation into complex scaffolds, making it a reliable component for constructing bioactive molecules and advanced intermediates.

Synthesis

  • Route1
    • In-stock
      1-(5-Bromo-2-hydroxyphenyl)ethanone|CS-W007495
      1450-75-5
    • ~65%
    • In-stock
      5-Bromo-2-methyl-1,3-benzoxazole|CS-W005533
      5676-56-2
    • null|null
      42524-21-0

    References

    • Tetrahedron Letters, , vol. 52, # 46 p. 6103 - 6107
  • Route2
    • null|null
      1445-45-0
    • In-stock
      4-Bromo-2-nitrophenol|CS-W007763
      7693-52-9
    • ~94%
    • In-stock
      5-Bromo-2-methyl-1,3-benzoxazole|CS-W005533
      5676-56-2

    References

    • Tetrahedron, , vol. 65, # 43 p. 8821 - 8831
  • Route3
    • null|null
      1445-45-0
    • In-stock
      2-Amino-4-bromophenol|CS-W007625
      40925-68-6
    • ~%
    • In-stock
      5-Bromo-2-methyl-1,3-benzoxazole|CS-W005533
      5676-56-2

    References

    • WO2003/99776 A1, ; Page 56 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   26.03
  • LogP   2.89872
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Bromo-2-methyl-1,3-benzoxazole sigma5-Bromo-2-methyl-1,3-benzoxazole manufacturer5-Bromo-2-methyl-1,3-benzoxazole price5-Bromo-2-methyl-1,3-benzoxazole structure5-Bromo-2-methyl-1,3-benzoxazole SDSbuy 5-Bromo-2-methyl-1,3-benzoxazole5-Bromo-2-methyl-1,3-benzoxazole supplier5-Bromo-2-methyl-1,3-benzoxazole uses5-Bromo-2-methyl-1,3-benzoxazole molecular weightprice of 5-Bromo-2-methyl-1,3-benzoxazole5-Bromo-2-methyl-1,3-benzoxazole chemical name formula of 5-Bromo-2-methyl-1,3-benzoxazole
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label