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CS-W001157 4
Total: USD 88.00

(R)-(-)-2-Phenylglycinol

  • CAS No. 56613-80-0

  • Cat. No. CS-W002038
  • Purity≥97%
  • MDL No.MFCD00008062

*For research and further manufacturing use only, not for direct human use.

(R)-(-)-2-Phenylglycinol|CS-W002038

Structure of 56613-80-0

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General Information

  • CAS No. 56613-80-0
  • Cat. No. CS-W002038
  • Purity ≥97%
  • MDL No. MFCD00008062
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁NO
  • Molecular Weight 137.18
  • Synonym(s) D-Phenylglycinol; (-)-Phenylglycinol
  • SMILES N[C@@H](CO)C1=CC=CC=C1

Description

Amino alcohol used to prepare a chiral imine or oxazolidine from ethyl trifluoropyruvate. These intermediates were then employed in a synthesis of both enantiomers of -trifluoromethylproline.

Synthesis

  • Route1
    • H-D-Phg-OH Ampicillin Impurity|CS-0229771
      875-74-1
    • ~92%
    • In-stock
      (R)-(-)-2-Phenylglycinol|CS-W002038
      56613-80-0

    References

    • Shi, Xin; He, Wei; Li, Hua; Zhang, Xu; Zhang, Shengyong Tetrahedron Letters, 2011 , vol. 52, # 25 p. 3204 - 3207
  • Route2
    • Phenylglycine Procaterol  Impurity|CS-0228864
      103-01-5
    • ~%
    • In-stock
      (R)-(-)-2-Phenylglycinol|CS-W002038
      56613-80-0

    References

    • US6399643 B1, ;
  • Route3
    • (R)-Methyl 2-amino-2-phenylacetate|CS-0356354
      24461-61-8
    • ~65%
    • In-stock
      (R)-(-)-2-Phenylglycinol|CS-W002038
      56613-80-0

    References

    • Kamer; Cleij; Nolte; Harada; Hezemans; Drenth Journal of the American Chemical Society, 1988 , vol. 110, # 5 p. 1581 - 1587

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   0.6787
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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