Lot numbers can be found on the outside label of a product:
Octahydropyrrolo[1,2-a]pyrazine
-
CAS No. 5654-83-1
- Cat. No. CS-0002040
- Purity≥98%
- MDL No.MFCD00082600
*For research and further manufacturing use only, not for direct human use.
![Octahydropyrrolo[1,2-a]pyrazine|CS-0002040](https://file.chemscene.com/productPIC/CS-0002040.gif)
Structure of 5654-83-1
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 5654-83-1
- Cat. No. CS-0002040
- Purity ≥98%
- MDL No. MFCD00082600
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₇H₁₄N₂
- Molecular Weight 126.20
- Synonym(s) Octahydro-pyrrolo[1,2-a]pyrazine 2HCl
- SMILES N1(CCC2)C2CNCC1
Description
Octahydropyrrolo[1,2-a]pyrazine is a saturated heterocyclic scaffold featuring two nitrogen atoms in a fused ring system, offering enhanced solubility and metabolic stability. This rigid, electron-rich framework integrates readily into bioactive molecules, serving as a conformationally constrained core for medicinal chemistry applications.
Application
Octahydropyrrolo[1,2-a]pyrazine serves as a versatile saturated heterocyclic scaffold in medicinal chemistry, offering a rigid, nitrogen-rich core with defined stereochemistry. Its amine functionalities enable straightforward derivatization via alkylation, acylation, and reductive amination, facilitating rapid access to diverse analogs. The compound exhibits excellent bench stability and compatibility with standard purification techniques, making it a practical building block for targeted library synthesis.
Synthesis
-
Route1
-
In-stock
19179-12-5 - ~62%
-
In-stock
5654-83-1
References
-
MEMORY PHARMACEUTICALS CORPORATION Patent: US2008/200471 A1, 2008 ; Location in patent: Page/Page column 37; 37-38 ; US 20080200471 A1
-
-
Route2
-
71257-37-9 - ~79%
-
In-stock
5654-83-1
References
-
Likhosherstov, A. M.; Peresada, V. P.; Skoldinov, A. P. Pharmaceutical Chemistry Journal, 1993 , vol. 27, # 10 p. 716 - 718 Khimiko-Farmatsevticheskii Zhurnal, 1993 , vol. 27, # 10 p. 46 - 48
-
-
Route3
-
88327-63-3
- ~40%
-
In-stock
5654-83-1
References
-
Shukla, U. K.; Khanna, J. M.; Sharma, Satyavan; Anand, Nitya; Chatterjee, R. K.; Sen, A. B. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 7 p. 664 - 668
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS05
|
|
Signal Word : Danger
|
UN#: 3267
|
|
Class : 8
|
Packing Group : Ⅲ
|
|
Hazard Statements : H314
|
|
|
Precautionary Statements : P264-P271-P280-P301+P330+P331-P304+P340-P363-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 15.27
- LogP 0.054
- H_Acceptors 2
- H_Donors 1
- Rotatable_Bonds 0
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Octahydropyrrolo[1,2-a]pyrazine sigmaOctahydropyrrolo[1,2-a]pyrazine manufacturerOctahydropyrrolo[1,2-a]pyrazine priceOctahydropyrrolo[1,2-a]pyrazine structureOctahydropyrrolo[1,2-a]pyrazine SDSbuy Octahydropyrrolo[1,2-a]pyrazineOctahydropyrrolo[1,2-a]pyrazine supplierOctahydropyrrolo[1,2-a]pyrazine usesOctahydropyrrolo[1,2-a]pyrazine molecular weightprice of Octahydropyrrolo[1,2-a]pyrazineOctahydropyrrolo[1,2-a]pyrazine chemical name formula of Octahydropyrrolo[1,2-a]pyrazine