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Structure of 5653-88-3
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This malonate derivative features a phenylmethylene group integrated at the C2 position, enhancing conjugation and electronic delocalization. The molecule combines a rigid aromatic moiety with a reactive dicarboxylic acid core, enabling efficient coupling in synthetic transformations. Its stability under standard conditions supports use in multistep syntheses and modular derivatization workflows.
2-(Phenylmethylene)butanedioic acid serves as a versatile diacid building block for the synthesis of heterocyclic scaffolds and bioactive molecules. Its conjugated enone-like system enables Diels-Alder cycloadditions and Michael additions, while the carboxylic acid groups facilitate derivatization and metal coordination. The compound exhibits good bench stability and is amenable to purification via recrystallization, making it well-suited for use in iterative synthetic sequences and medicinal chemistry campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: