8-Chloro-3-methylimidazo[1,5-a]pyrazine

Name: 8-Chloro-3-methylimidazo[1,5-a]pyrazine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 56468-24-7
Cat. No. CS-0197288
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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8-Chloro-3-methylimidazo[1,5-a]pyrazine|CS-0197288

Structure of 56468-24-7

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Description

8-Chloro-3-methylimidazo[1,5-a]pyrazine is a heterocyclic scaffold featuring a chlorinated imidazopyrazine core with a methyl substituent at the 3-position. This electron-deficient system enables direct incorporation into pharmaceutical intermediates and agrochemicals, offering enhanced metabolic stability and tunable reactivity under standard coupling conditions.

Application

8-Chloro-3-methylimidazo[1,5-a]pyrazine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient construction of bioactive scaffolds. Its functionalized imidazopyrazine core exhibits robust bench stability and compatibility with standard coupling reactions, facilitating downstream derivatization. The chlorine and methyl groups provide orthogonal handles for selective functionalization, enhancing utility in the synthesis of pharmaceutical intermediates and target-oriented libraries.

General Information

CAS No. 56468-24-7
Cat. No. CS-0197288
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆ClN₃
Molecular Weight 167.60
Synonym(s) 8-Chloro-3-methyl-imidazo[1,5-a]pyrazine
SMILES CC1=NC=C2C(Cl)=NC=CN21

Computational Chemistry Data

TPSA 30.19
LogP 1.69112
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazine compounds

Key Words

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8-Chloro-3-methylimidazo[1,5-a]pyrazine

CAS No. 56468-24-7

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