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Structure of 56453-86-2
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(E)-3-Cyclohexylacrylic acid is a sterically defined, bench-stable α,β-unsaturated carboxylic acid featuring a conjugated trans double bond. This configuration enhances its utility in Michael additions and Diels-Alder reactions, where geometric control is critical. The cyclohexyl group imparts hydrophobic character and conformational rigidity, enabling precise spatial positioning in synthetic intermediates. Its moisture-tolerant stability simplifies handling under standard laboratory conditions.
(E)-3-Cyclohexylacrylic acid serves as a versatile building block for synthesizing α,β-unsaturated carboxylic acids and their derivatives. Its conjugated double bond enables reliable Michael additions, Diels–Alder reactions, and palladium-catalyzed couplings. The cyclohexyl group imparts steric bulk and lipophilicity, enhancing metabolic stability in bioactive molecule design. Bench-stable and readily purified by recrystallization, it functions effectively in standard organic transformations.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: