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CS-W001157 4
Total: USD 88.00

4-Methyl-N,N-bis(2-(4-methylphenylsulfonamido)ethyl)benzenesulfonamide

  • CAS No. 56187-04-3

  • Cat. No. CS-0153024
  • Purity≥97%
  • MDL No.MFCD00015623

*For research and further manufacturing use only, not for direct human use.

4-Methyl-N,N-bis(2-(4-methylphenylsulfonamido)ethyl)benzenesulfonamide|CS-0153024

Structure of 56187-04-3

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General Information

  • CAS No. 56187-04-3
  • Cat. No. CS-0153024
  • Purity ≥97%
  • MDL No. MFCD00015623
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₅H₃₁N₃O₆S₃
  • Molecular Weight 565.73
  • Synonym(s) N,N',N''-Tritosyldiethylenetriamine
  • SMILES CC1=CC=C(C=C1)S(=O)(=O)NCCN(CCNS(=O)(=O)C2=CC=C(C)C=C2)S(=O)(=O)C3=CC=C(C)C=C3

Description

This sulfonamide derivative features a rigid, electron-deficient aromatic core flanked by sterically hindered bis(alkylsulfonamido) side chains, enabling robust integration into high-performance pharmaceutical scaffolds. Designed for enhanced metabolic stability and solubility under standard conditions, it serves as a key building block in targeted kinase inhibitor development.

Synthesis

  • Route1
    • null|null
      111-40-0
    • null|null
      98-59-9
    • ~98%
    • In-stock
      4-Methyl-N,N-bis(2-(4-methylphenylsulfonamido)ethyl)benzenesulfonamide|CS-0153024
      56187-04-3

    References

    • Wilson, Jennifer M.; Giordani, Federica; Farrugia, Louis J.; Barrett, Michael P.; Robins, David J.; Sutherland, Andrew Organic and Biomolecular Chemistry, 2007 , vol. 5, # 22 p. 3651 - 3656
  • Route2
    • null|null
      7732-18-5
    • null|null
      111-40-0
    • null|null
      98-59-9
    • ~92%
    • In-stock
      4-Methyl-N,N-bis(2-(4-methylphenylsulfonamido)ethyl)benzenesulfonamide|CS-0153024
      56187-04-3

    References

    • Monsanto Company Patent: US5610293 A1, 1997 ;
  • Route3
    • null|null
      111-40-0
    • null|null
      98-59-9
    • ~9%
    • In-stock
      4-Methyl-N,N-bis(2-(4-methylphenylsulfonamido)ethyl)benzenesulfonamide|CS-0153024
      56187-04-3
    • null|null
      77429-97-1

    References

    • Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, , vol. 62, # 3 p. 397 - 406

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H413
Precautionary Statements : P264-P273-P280-P302+P352-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   129.72
  • LogP   2.55956
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   12

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