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Structure of 561314-52-1
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1,3,8-Triazaspiro[4.5]decan-2-one is a rigid, nitrogen-rich spirocyclic scaffold featuring three contiguous heteroatoms within a constrained bicyclic framework. This architecture imparts high thermal stability and enhanced solubility in polar solvents, enabling its use as a privileged core in medicinal chemistry. The molecule integrates seamlessly into bioactive compound libraries, particularly for targeting protein-protein interactions where conformational rigidity improves binding affinity.
1,3,8-Triazaspiro[4.5]decan-2-one serves as a versatile scaffold for medicinal chemistry and catalytic synthesis, featuring a rigid spirocyclic framework with three nitrogen atoms enabling diverse functionalization. Its stability under standard reaction conditions and compatibility with common protecting group strategies facilitate efficient access to complex heterocycles. The molecule functions as a key building block in the construction of bioactive compounds, particularly in the development of kinase inhibitors and CNS-targeted pharmaceuticals.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: