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CS-W001157 4
Total: USD 88.00

1-Bromo-2-chloro-3-(trifluoromethyl)benzene

  • CAS No. 56131-47-6

  • Cat. No. CS-W014599
  • Purity≥97%
  • MDL No.MFCD04115994

*For research and further manufacturing use only, not for direct human use.

1-Bromo-2-chloro-3-(trifluoromethyl)benzene|CS-W014599

Structure of 56131-47-6

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General Information

  • CAS No. 56131-47-6
  • Cat. No. CS-W014599
  • Purity ≥97%
  • MDL No. MFCD04115994
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₃BrClF₃
  • Molecular Weight 259.45
  • Synonym(s) 3-Bromo-2-chlorobenzotrifluoride
  • SMILES FC(C1=C(Cl)C(Br)=CC=C1)(F)F

Description

1-Bromo-2-chloro-3-(trifluoromethyl)benzene features a trifluoromethyl group flanked by bromo and chloro substituents on a benzene ring, enabling selective cross-coupling reactions. This electron-deficient aryl halide integrates readily into complex molecular architectures under standard conditions.

Application

1-Bromo-2-chloro-3-(trifluoromethyl)benzene serves as a versatile building block in cross-coupling reactions, enabling efficient construction of complex aryl architectures. The ortho-bromochloro substitution pattern provides complementary reactivity for sequential functionalization, while the trifluoromethyl group enhances metabolic stability and lipophilicity. Its bench-stable nature and compatibility with Pd-catalyzed couplings facilitate reliable synthesis of pharmaceutical intermediates and agrochemical scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   4.1213
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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