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Structure of 55849-30-4
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3-Bromo-6-ethoxypyridine features a pyridine core functionalized with bromine at the 3-position and ethoxy at the 6-position, enabling direct coupling in cross-coupling reactions. The electron-deficient ring facilitates palladium-catalyzed transformations, while the ethoxy group enhances solubility and modulates reactivity. This compound serves as a key intermediate in pharmaceutical synthesis.
3-Bromo-6-ethoxypyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-established reactivity profile. The bromo group facilitates C–C bond formation under standard Suzuki, Stille, or Negishi conditions, while the ethoxy substituent provides moderate electron-withdrawing character and enhances solubility. This compound exhibits bench stability, ease of handling, and compatibility with common protecting group strategies, making it suitable for iterative synthesis of complex heterocyclic scaffolds.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H317-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P272-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: