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Structure of 55805-20-4
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3-(Difluoromethyl)benzoic acid features a difluoromethyl group ortho to the carboxylic acid, enhancing metabolic stability and modulating electronic properties. This substitution imparts favorable lipophilicity and electron-withdrawing character, making it valuable for medicinal chemistry applications where improved bioavailability and target engagement are critical.
3-(Difluoromethyl)benzoic acid serves as a valuable building block in medicinal chemistry, enabling the incorporation of a difluoromethyl group adjacent to a carboxylic acid functionality. The molecule exhibits enhanced metabolic stability and modulates electronic properties through the electron-withdrawing difluoromethyl substituent. It functions effectively in standard coupling reactions and participates in derivatization protocols for heterocyclic scaffolds, offering predictable reactivity and bench stability under routine handling conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: