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CS-W001157 4
Total: USD 88.00

(tert-Butoxycarbonyl)-D-isoleucine

  • CAS No. 55721-65-8

  • Cat. No. CS-0158738
  • Purity≥95%
  • MDL No.MFCD00069989

*For research and further manufacturing use only, not for direct human use.

(tert-Butoxycarbonyl)-D-isoleucine|CS-0158738

Structure of 55721-65-8

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General Information

  • CAS No. 55721-65-8
  • Cat. No. CS-0158738
  • Purity ≥95%
  • MDL No. MFCD00069989
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₁NO₄
  • Molecular Weight 231.29
  • Synonym(s) N-tert-Butyloxycarbonyl-D-isoleucine
  • SMILES CC[C@@H](C)[C@H](C(O)=O)NC(OC(C)(C)C)=O

Description

Boc-D-isoleucine serves as a protected amino acid building block for peptide synthesis, featuring a sterically hindered tert-butoxycarbonyl group that ensures stability during coupling reactions. This derivative enables selective N-terminal protection and facilitates efficient chain elongation under standard conditions.

Application

Boc-D-isoleucine serves as a key chiral building block in peptide synthesis, enabling efficient N-terminal protection with high stability under acidic conditions. Its tert-butoxycarbonyl group facilitates orthogonal deprotection in standard SPPS workflows, while the D-isoleucine side chain provides structural rigidity and resistance to enzymatic degradation. The compound exhibits excellent bench stability, minimal racemization during coupling, and compatibility with diverse activation methods.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   2.0104
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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