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CS-W001157 4
Total: USD 88.00

(4-Chlorophenyl)-4-piperidinylmethanone Hydrochloride

  • CAS No. 55695-51-7

  • Cat. No. CS-W002259
  • Molecule weight260.16
  • Purity≥98%
  • MDL No.MFCD00053028

*For research and further manufacturing use only, not for direct human use.

(4-Chlorophenyl)-4-piperidinylmethanone Hydrochloride|CS-W002259

Structure of 55695-51-7

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General Information

  • CAS No. 55695-51-7
  • Cat. No. CS-W002259
  • Purity ≥98%
  • MDL No. MFCD00053028
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₅Cl₂NO
  • Molecular Weight 260.16
  • Synonym(s) (4-Chlorophenyl)(piperidin-4-yl)methanone hydrochloride
  • SMILES O=C(C1=CC=C(Cl)C=C1)C2CCNCC2.Cl

Description

This piperidine-based ketone features a 4-chlorophenyl substituent that enhances electron-withdrawing character and improves metabolic stability. The hydrochloride salt form ensures excellent solubility and handling convenience in aqueous reaction media. This compound serves as a key scaffold in medicinal chemistry for designing CNS-targeted therapeutics, particularly in opioid receptor ligand development.

Application

(4-Chlorophenyl)-4-piperidinylmethanone Hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its piperidine amide functionality offers enhanced solubility and metabolic stability, while the para-chlorophenyl group provides a handle for further functionalization via cross-coupling or nucleophilic substitution. The hydrochloride salt enhances bench stability and facilitates purification, making it well-suited for scalable synthesis and API intermediate development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   2.9441
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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