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Structure of 556112-92-6
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Methyl 2-fluoro-5-(trifluoromethyl)benzoate features a fluorinated aromatic core with orthogonal electron-withdrawing trifluoromethyl and fluoro substituents, enabling enhanced metabolic stability and tailored lipophilicity. This ortho-fluorinated ester integrates readily into synthetic routes for bioactive molecules, particularly in medicinal chemistry applications requiring precise electronic modulation.
Methyl 2-fluoro-5-(trifluoromethyl)benzoate serves as a versatile building block in medicinal chemistry, enabling efficient access to fluorinated aromatic scaffolds. Its orthogonal functional groups—fluorine and trifluoromethyl—facilitate selective transformations, while the ester moiety supports downstream derivatization. The compound exhibits excellent bench stability and compatibility with standard coupling reactions, making it well-suited for iterative synthesis campaigns in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: