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Propan-1-amine hydrochloride

  • CAS No. 556-53-6

  • Cat. No. CS-0079898
  • Purity≥97%
  • MDL No.MFCD00012911

*For research and further manufacturing use only, not for direct human use.

Propan-1-amine hydrochloride|CS-0079898

Structure of 556-53-6

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General Information

  • CAS No. 556-53-6
  • Cat. No. CS-0079898
  • Purity ≥97%
  • MDL No. MFCD00012911
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₁₀ClN
  • Molecular Weight 95.57
  • Synonym(s) Propylammonium Chloride
  • SMILES CCCN.[H]Cl

Description

Propylamine hydrochloride was used to study the liquid chromatographic behavior of potassium-sparing and loop diuretics.

Application

Propan-1-amine hydrochloride serves as a versatile primary amine source in synthetic organic chemistry, enabling efficient amidation, alkylation, and reductive amination reactions. Its crystalline form ensures excellent bench stability and ease of handling, while the hydrochloride salt facilitates purification via acid-base workup. This reagent functions reliably in the construction of pharmaceutical intermediates and heterocyclic scaffolds, offering broad functional group tolerance in standard reaction conditions.

Synthesis

  • Route1
    • null|null
      108-03-2
    • ~84%
    • In-stock
      Propan-1-amine hydrochloride|CS-0079898
      556-53-6

    References

    • Gowda, Shankare; Gowda, D. Channe Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2003 , vol. 42, # 1 p. 180 - 183
  • Route2

    References

    • Miyamoto, Kazunori; Sakai, Yuuta; Goda, Shunsuke; Ochiai, Masahito Chemical Communications, 2012 , vol. 48, # 7 p. 982 - 984
  • Route3
    • null|null
      51411-25-7
    • ~%
    • In-stock
      Propan-1-amine hydrochloride|CS-0079898
      556-53-6

    References

    • Organic Letters, , vol. 1, # 9 p. 1395 - 1397

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   0.7769
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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