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CS-W001157 4
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3-(Methylsulfonamido)benzaldehyde

  • CAS No. 55512-05-5

  • Cat. No. CS-0150124
  • Purity≥97%
  • MDL No.MFCD03198179

*For research and further manufacturing use only, not for direct human use.

3-(Methylsulfonamido)benzaldehyde|CS-0150124

Structure of 55512-05-5

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General Information

  • CAS No. 55512-05-5
  • Cat. No. CS-0150124
  • Purity ≥97%
  • MDL No. MFCD03198179
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₃S
  • Molecular Weight 199.23
  • Synonym(s) N-(3-formylphenyl)methanesulfonamide
  • SMILES CS(=O)(=O)NC1=CC=CC(=C1)C=O

Description

3-(Methylsulfonamido)benzaldehyde features a para-substituted benzaldehyde core bearing a methylsulfonamido group, delivering enhanced solubility and stability in polar reaction media. This electron-withdrawing moiety facilitates efficient coupling reactions, particularly in the synthesis of bioactive heterocycles and pharmaceutical intermediates under standard conditions.

Application

3-(Methylsulfonamido)benzaldehyde serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles and pharmaceutical scaffolds. Its aldehyde functionality facilitates efficient condensation reactions, while the sulfonamide group provides hydrogen-bonding capability and metabolic stability. The compound exhibits good bench stability and compatibility with standard functional group transformations, making it well-suited for iterative synthesis campaigns in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   63.24
  • LogP   0.8706
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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