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CS-W001157 4
Total: USD 88.00

Tiliquinol

  • CAS No. 5541-67-3

  • Cat. No. CS-W019183
  • Purity≥98%
  • MDL No.MFCD00864652

*For research and further manufacturing use only, not for direct human use.

Tiliquinol|CS-W019183

Structure of 5541-67-3

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General Information

  • CAS No. 5541-67-3
  • Cat. No. CS-W019183
  • Purity ≥98%
  • MDL No. MFCD00864652
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₉NO
  • Molecular Weight None
  • Synonym(s) NSC 130828
  • SMILES OC1=C2N=CC=CC2=C(C)C=C1

Description

Tiliquinol delivers a potent, electron-rich scaffold for medicinal chemistry, featuring a fused quinoline core with strategic hydroxyl and methoxy groups. This bench-stable compound integrates readily into bioactive molecule design, offering enhanced solubility and metabolic stability in complex synthetic sequences.

Application

Tiliquinol serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through its phenolic and quinoline functionalities. Its stability under standard reaction conditions and compatibility with diverse coupling protocols facilitate efficient access to complex scaffolds. The molecule functions as a key intermediate in the development of kinase inhibitors and other pharmacologically relevant compounds, offering predictable reactivity for downstream derivatization.

Synthesis

  • Route1
    • 8-Methoxy-5-methylquinoline|CS-0871459
      126403-57-4
    • ~%
    • In-stock
      Tiliquinol|CS-W019183
      5541-67-3

    References

    • Synthetic Communications, , vol. 19, # 13-14 p. 2273 - 2282
  • Route2

    References

    • Journal of the Chemical Society, , p. 4391
  • Route3
    • null|null
      119-33-5
    • ~%
    • In-stock
      Tiliquinol|CS-W019183
      5541-67-3

    References

    • Journal fuer Praktische Chemie (Leipzig), , vol. 323, # 6 p. 979 - 984

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   2.24882
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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