Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

6-(4-Methylpiperazin-1-yl)pyridin-3-amine

  • CAS No. 55403-35-5

  • Cat. No. CS-0036514
  • Purity≥97%
  • MDL No.MFCD03425719

*For research and further manufacturing use only, not for direct human use.

6-(4-Methylpiperazin-1-yl)pyridin-3-amine|CS-0036514

Structure of 55403-35-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 55403-35-5
  • Cat. No. CS-0036514
  • Purity ≥97%
  • MDL No. MFCD03425719
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₆N₄
  • Molecular Weight 192.26
  • Synonym(s) 3-Amino-6-(4-methyl-1-piperazinyl)pyridine
  • SMILES CN1CCN(CC1)C2=CC=C(C=N2)N

Description

This pyridine-based amine integrates a 4-methylpiperazinyl group at the 6-position, delivering enhanced solubility and nucleophilicity. The electron-rich piperazine moiety facilitates efficient coupling reactions, while the pendant amine enables straightforward derivatization. Ideal for constructing bioactive scaffolds in medicinal chemistry applications.

Application

6-(4-Methylpiperazin-1-yl)pyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its pyridine core provides favorable solubility and metabolic stability, while the piperazine moiety offers multiple sites for derivatization. The compound exhibits bench stability and compatibility with common purification methods, facilitating its use in parallel synthesis campaigns and lead optimization workflows.

Synthesis

  • Route1

    References

    • Tsou, Hwei-Ru; Otteng, Mercy; Tran, Tritin; Floyd Jr., M. Brawner; Reich, Marvin; Birnberg, Gary; Kutterer, Kristina; Ayral-Kaloustian, Semiramis; Ravi, Malini; Nilakantan, Ramaswamy; Grillo, Mary; McGinnis, John P.; Rabindran, Sridhar K. Journal of Medicinal Chemistry, 2008 , vol. 51, # 12 p. 3507 - 3525
  • Route2

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 5 p. 1362 - 1365
  • Route3

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 5 p. 1362 - 1365

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   45.39
  • LogP   0.4156
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 55403-35-5 sigma55403-35-5 manufacturer55403-35-5 price55403-35-5 structure55403-35-5 SDSbuy 55403-35-555403-35-5 supplier55403-35-5 uses55403-35-5 molecular weightprice of 55403-35-555403-35-5 chemical name formula of 55403-35-5
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label