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CS-W001157 4
Total: USD 88.00

T-1105

  • CAS No. 55321-99-8

  • Cat. No. CS-W016480
  • Purity≥96%
  • MDL No.MFCD00233977

*For research and further manufacturing use only, not for direct human use.

T-1105|CS-W016480

Structure of 55321-99-8

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General Information

  • CAS No. 55321-99-8
  • Cat. No. CS-W016480
  • Purity ≥96%
  • MDL No. MFCD00233977
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅N₃O₂
  • Molecular Weight None
  • Synonym(s) None
  • SMILES O=C(C1=NC=CN=C1O)N

Description

T-1105 features a sterically hindered, bench-stable boronate moiety that enables reliable coupling in Suzuki-Miyaura reactions. This electron-deficient arylborane integrates seamlessly into complex molecular architectures under mild conditions, offering enhanced functional group tolerance and predictable reactivity for synthetic chemists developing pharmaceutical intermediates.

Application

T-1105 serves as a robust building block for constructing nitrogen-containing heterocycles, particularly pyrrolidines and piperidines, via facile cyclization under mild conditions. Its well-defined reactivity enables efficient functional group interconversions, exhibits excellent bench stability, and facilitates straightforward purification—making it ideal for iterative synthesis workflows in medicinal chemistry and process development.

Synthesis

  • Route1
    • null|null
      131543-46-9
    • Aminomalonamide Favipiravir  Impurity|CS-0228980
      62009-47-6
    • ~64%
    • In-stock
      T-1105|CS-W016480
      55321-99-8

    References

    • Pierra, Claire; Counor, Clement; Storer, Richard; Gosselin, Gilles Collection of Czechoslovak Chemical Communications, 2011 , vol. 76, # 11 p. 1327 - 1333
  • Route2

    References

    • Journal of the American Chemical Society, , vol. 69, p. 1034,1035 Journal of the American Chemical Society, , vol. 74, p. 3617,3618,3620
  • Route3

    References

    • Journal of the American Chemical Society, , vol. 69, p. 1034,1035

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   89.1
  • LogP   -0.7189
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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