2,6-Dibromonicotinaldehyde

Name: 2,6-Dibromonicotinaldehyde
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 55304-83-1
Cat. No. CS-0052135
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 55304-83-1

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 55304-83-1
Cat. No. CS-0052135
Purity ≥97%
MDL No. None
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₃Br₂NO
Molecular Weight 264.90
Synonym(s) 2,6-Dibromopyridine-3-carbaldehyde
SMILES O=CC1=CC=C(N=C1Br)Br

Description

2,6-Dibromonicotinaldehyde features a pyridine ring flanked by bromine substituents at the 2 and 6 positions, delivering a highly electron-deficient aldehyde moiety. This configuration enhances reactivity in cross-coupling processes while maintaining stability under standard handling conditions. The dibromo substitution pattern enables selective functionalization in synthetic sequences requiring orthogonal reactivity.

Application

2,6-Dibromonicotinaldehyde serves as a versatile building block in heterocyclic synthesis, enabling direct functionalization at the 3- and 5-positions of the pyridine ring. Its aldehyde functionality facilitates imine formation and reductive amination, while the bromine substituents support palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Stille couplings. The molecule exhibits good bench stability and is compatible with standard purification techniques, making it suitable for use in medicinal chemistry campaigns and advanced synthetic sequences requiring orthogonally reactive handles.

Synthesis

Route1
- In-stock
  
  626-05-1
- 107-31-3
- ~%
- In-stock
  
  55304-83-1
References
- WO2006/21848 A1, ; Page/Page column 30 ; WO 2006/021848 A1
Route2
- In-stock
  
  626-05-1
- 68-12-2
- ~%
- 109-04-6
- In-stock
  
  34160-40-2
- In-stock
  
  55304-83-1
References
- Journal of Organic Chemistry, , vol. 66, # 20 p. 6775 - 6786

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 29.96
LogP 2.4191
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

2,6-Dibromonicotinaldehyde sigma2,6-Dibromonicotinaldehyde manufacturer2,6-Dibromonicotinaldehyde price2,6-Dibromonicotinaldehyde structure2,6-Dibromonicotinaldehyde SDSbuy 2,6-Dibromonicotinaldehyde2,6-Dibromonicotinaldehyde supplier2,6-Dibromonicotinaldehyde uses2,6-Dibromonicotinaldehyde molecular weightprice of 2,6-Dibromonicotinaldehyde2,6-Dibromonicotinaldehyde chemical name formula of 2,6-Dibromonicotinaldehyde

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2,6-Dibromonicotinaldehyde

CAS No. 55304-83-1

Recommended Products