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Structure of 55240-51-2
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2-Phenylisonicotinic acid features a rigid, planar architecture with orthogonal aromatic rings that enhance conjugation and electronic delocalization. This structural rigidity supports applications in ligand design and pharmaceutical scaffolding where defined spatial orientation is critical.
2-Phenylisonicotinic acid serves as a versatile building block in medicinal chemistry, enabling the construction of biologically active heterocyclic scaffolds. Its ortho-phenyl substitution enhances rigidity and modulates electronic properties, facilitating efficient coupling reactions in amide bond formation and transition-metal-catalyzed transformations. The carboxylic acid functionality provides reliable handle for derivatization, while the compound exhibits good bench stability and ease of purification—ideal for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: