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Structure of 552301-45-8
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This sterically hindered carboxylic acid features a hydroxyethyl-substituted phenyl ring, enabling direct conjugation or derivatization in synthetic workflows. The pendant hydroxyl group facilitates hydrogen bonding and enhances solubility in polar media, while the methylpropanoate backbone ensures stability under standard bench conditions.
2-(4-(2-Hydroxyethyl)phenyl)-2-methylpropanoic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive scaffolds through its orthogonal functional groups. The carboxylic acid facilitates amide coupling, while the pendant hydroxyl group supports derivatization via esterification or ether formation. Its benzylic methyl substitution enhances metabolic stability, and the overall structure exhibits favorable bench stability and ease of purification in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P260-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: