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CS-W001157 4
Total: USD 88.00

6-Methylpyrazine-2-carboxylic acid

  • CAS No. 5521-61-9

  • Cat. No. CS-W003558
  • Purity≥97%
  • MDL No.MFCD08705756

*For research and further manufacturing use only, not for direct human use.

6-Methylpyrazine-2-carboxylic acid|CS-W003558

Structure of 5521-61-9

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General Information

  • CAS No. 5521-61-9
  • Cat. No. CS-W003558
  • Purity ≥97%
  • MDL No. MFCD08705756
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆N₂O₂
  • Molecular Weight 138.12
  • Synonym(s) Glipizide Impurity 8
  • SMILES Cc1cncc(n1)C(=O)O

Description

6-Methylpyrazine-2-carboxylic acid features a pyrazine core with complementary methyl and carboxylic acid functionalities, enabling direct integration into heterocyclic scaffolds. This electron-deficient heterocycle facilitates coupling reactions under mild conditions, offering enhanced stability and solubility in polar media for applications in medicinal chemistry and agrochemical synthesis.

Application

6-Methylpyrazine-2-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and agrochemical research, enabling efficient access to pyrazine-based scaffolds. Its carboxylic acid functionality facilitates direct derivatization via amide coupling, esterification, or decarboxylation protocols, while the methyl and pyrazine core offer favorable stability and orthogonal reactivity. The compound exhibits excellent bench stability and compatibility with standard purification techniques, making it well-suited for modular synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.08
  • LogP   0.48322
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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