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CS-W001157 4
Total: USD 88.00

m-PEG5-NH2

  • CAS No. 5498-83-9

  • Cat. No. CS-0114797
  • Purity≥97%
  • MDL No.MFCD27977523

*For research and further manufacturing use only, not for direct human use.

m-PEG5-NH2|CS-0114797

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General Information

  • CAS No. 5498-83-9
  • Cat. No. CS-0114797
  • Purity ≥97%
  • MDL No. MFCD27977523
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₅NO₅
  • Molecular Weight 251.32
  • Synonym(s) None
  • SMILES COCCOCCOCCOCCOCCN

Description

m-PEG5-NH2 features a five-unit polyethylene glycol chain linked to a primary amine group, offering enhanced solubility and stability in aqueous environments. This bifunctional scaffold enables efficient conjugation in bioconjugation workflows, where the terminal amine facilitates coupling reactions with carboxylated biomolecules or activated esters.

Application

m-PEG5-NH₂ serves as a versatile bifunctional linker for conjugation and polymer synthesis, offering controlled hydrophilicity and precise chain length. Its terminal primary amine enables efficient coupling to carboxylated biomolecules, while the central PEG5 spacer provides excellent solubility, stability, and reduced non-specific binding. Ideal for bioconjugation, drug delivery systems, and surface functionalization, it facilitates straightforward purification and maintains performance across diverse reaction conditions.

Synthesis

  • Route1

    References

    • Journal of the American Chemical Society, , vol. 116, # 12 p. 5057 - 5062
  • Route2
    • m-PEG5-Tos|CS-0035504
      80755-67-5
    • ~%
    • In-stock
      m-PEG5-NH2|CS-0114797
      5498-83-9

    References

    • Journal of the American Chemical Society, , vol. 116, # 12 p. 5057 - 5062

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   72.17
  • LogP   -0.3421
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   14

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