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CS-W001157 4
Total: USD 88.00

2-Bromobenzimidazole

  • CAS No. 54624-57-6

  • Cat. No. CS-B1157
  • Purity≥98%
  • MDL No.MFCD00160009

*For research and further manufacturing use only, not for direct human use.

2-Bromobenzimidazole|CS-B1157

Structure of 54624-57-6

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General Information

  • CAS No. 54624-57-6
  • Cat. No. CS-B1157
  • Purity ≥98%
  • MDL No. MFCD00160009
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅BrN₂
  • Molecular Weight 197.03
  • Synonym(s) None
  • SMILES BrC1=NC2=CC=CC=C2N1

Description

2-Bromobenzimidazole is a bench-stable heterocyclic compound featuring a bromine substituent at the 2-position of the benzimidazole core. This electron-deficient scaffold integrates readily into synthetic sequences, serving as a key building block for bioactive molecules and functional materials. The bromine moiety enables efficient cross-coupling transformations, facilitating the construction of complex architectures in medicinal chemistry and materials science.

Application

2-Bromobenzimidazole serves as a versatile building block in medicinal chemistry and catalytic synthesis. Its bromine atom enables palladium-catalyzed cross-coupling reactions, facilitating the construction of biaryl architectures. The benzimidazole core provides a rigid, polar scaffold with favorable pharmacophoric properties, while the halogen offers high functional group tolerance and bench stability for downstream transformations.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   2.3254
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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