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Structure of 54621-18-0
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8-Amino-1,4-dioxaspiro[4.5]decane-8-carboxylic acid features a rigid spirocyclic scaffold that enhances metabolic stability while presenting a bifunctional handle: a primary amine and a carboxylic acid group positioned at the spirocenter. This spatially defined architecture enables site-specific conjugation in peptide synthesis and drug discovery applications. The molecule exhibits favorable solubility in aqueous and polar organic solvents under standard conditions.
8-Amino-1,4-dioxaspiro[4.5]decane-8-carboxylic acid serves as a versatile spirocyclic scaffold for medicinal chemistry applications, offering a rigid, three-dimensional core with orthogonal functional handles. The amino and carboxylic acid groups enable straightforward derivatization via amidation, alkylation, or reductive amination, while the spirocyclic framework imparts conformational stability and enhanced metabolic resistance. Its bench-stable crystalline nature facilitates purification and handling in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: