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Structure of 54620-70-1
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5-Hydroxypent-2-ynoic acid features a conjugated alkyne-carboxylic acid motif paired with a pendant hydroxyl group, enabling dual functionality in synthetic transformations. This scaffold supports efficient derivatization via click chemistry and offers enhanced solubility compared to non-hydroxylated analogs. The molecule exhibits stability under standard bench conditions and facilitates straightforward incorporation into bioconjugation workflows.
5-Hydroxypent-2-ynoic acid serves as a versatile building block for synthesizing α,β-unsaturated carbonyl systems and heterocyclic scaffolds. Its conjugated alkyne and carboxylic acid functionalities enable reliable transformations in Sonogashira coupling, cyclization reactions, and derivatization under mild conditions. The hydroxyl group provides additional handle for selective protection or functionalization, enhancing synthetic flexibility. This compound exhibits good bench stability and is readily purified by recrystallization or chromatography, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: