Lot numbers can be found on the outside label of a product:
6-Chloro-9-ethyl-9h-purine
-
CAS No. 5462-86-2
- Cat. No. CS-0216863
- Purity≥96%
- MDL No.None
*For research and further manufacturing use only, not for direct human use.
Structure of 5462-86-2
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 5462-86-2
- Cat. No. CS-0216863
- Purity ≥96%
- MDL No. None
- Storage -20°C, sealed storage, away from moisture
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₇H₇ClN₄
- Molecular Weight 182.61
- Synonym(s) 6-Chloro-9-ethylpurine
- SMILES CCN1C=NC2=C(Cl)N=CN=C21
Description
6-Chloro-9-ethyl-9H-purine is a bench-stable purine derivative featuring a chlorine atom at the 6-position and an ethyl group at the 9-position. This configuration imparts enhanced electronic modulation and improved solubility in organic solvents, facilitating its use in medicinal chemistry applications. The molecule serves as a key scaffold for synthesizing nucleoside analogs and kinase inhibitors.
Application
6-Chloro-9-ethyl-9H-purine serves as a versatile building block in purine-based synthesis, enabling efficient access to nucleoside analogs and heterocyclic scaffolds. Its chlorine at the 6-position provides a reliable site for palladium-catalyzed cross-coupling reactions, while the 9-ethyl group enhances solubility and stability under standard reaction conditions. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for medicinal chemistry campaigns and scale-up applications.
Synthesis
-
Route1
-
75-03-6 -
In-stock
87-42-3 - ~49%
-
In-stock
5462-86-2
References
-
Pharmacia and Upjohn S.p.A. Patent: US5965563 A1, 1999 ;
-
-
Route2
-
74-96-4
-
In-stock
87-42-3
- ~46%
-
In-stock
5462-86-2
-
74972-79-5
References
-
Zhang, Qian; Cheng, Gang; Huang, Yong-Zhen; Qu, Gui-Rong; Niu, Hong-Ying; Guo, Hai-Ming Tetrahedron, 2012 , vol. 68, # 38 p. 7822 - 7826
-
-
Route3
-
14036-06-7
-
In-stock
98140-03-5 - ~87%
-
In-stock
5462-86-2
References
-
Lambertucci, Catia; Antonini, Ippolito; Buccioni, Michela; Dal Ben, Diego; Kachare, Dhuldeo D.; Volpini, Rosaria; Klotz, Karl-Norbert; Cristalli, Gloria Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 7 p. 2812 - 2822
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 43.6
- LogP 1.4996
- H_Acceptors 4
- H_Donors 0
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 6-Chloro-9-ethyl-9h-purine sigma6-Chloro-9-ethyl-9h-purine manufacturer6-Chloro-9-ethyl-9h-purine price6-Chloro-9-ethyl-9h-purine structure6-Chloro-9-ethyl-9h-purine SDSbuy 6-Chloro-9-ethyl-9h-purine6-Chloro-9-ethyl-9h-purine supplier6-Chloro-9-ethyl-9h-purine uses6-Chloro-9-ethyl-9h-purine molecular weightprice of 6-Chloro-9-ethyl-9h-purine6-Chloro-9-ethyl-9h-purine chemical name formula of 6-Chloro-9-ethyl-9h-purine