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CS-W001157 4
Total: USD 88.00

2-Hydrazinopyrazine

  • CAS No. 54608-52-5

  • Cat. No. CS-M3641
  • Molecule weight110.12
  • Purity≥98%
  • MDL No.MFCD04114555

*For research and further manufacturing use only, not for direct human use.

2-Hydrazinopyrazine|CS-M3641

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General Information

  • CAS No. 54608-52-5
  • Cat. No. CS-M3641
  • Purity ≥98%
  • MDL No. MFCD04114555
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₆N₄
  • Molecular Weight 110.12
  • Synonym(s) 2-Hydrazinylpyrazine; 2-Hydrazinopyrazine; Hydrazinopyrazine; Pyrazinylhydrazine; 1-(pyrazin-2-yl)hydrazine
  • SMILES N/N=C1C=NC=CN/1

Description

2-Hydrazinopyrazine delivers a reactive hydrazino handle for conjugation chemistry, integrating readily into heterocyclic scaffolds. This bench-stable derivative features enhanced nucleophilicity at the pyrazine ring, enabling efficient coupling under mild conditions. Its electron-rich nature facilitates transition-metal-catalyzed transformations and supports applications in medicinal chemistry and materials science.

Application

2-Hydrazinopyrazine serves as a versatile building block in heterocyclic synthesis, enabling the construction of pyrazine-fused scaffolds through condensation and cyclization reactions. Its hydrazino functionality facilitates efficient metal-catalyzed couplings and acts as a key intermediate in the development of bioactive nitrogen-containing frameworks. The compound exhibits good bench stability and compatibility with common functional groups, supporting straightforward purification and integration into multi-step synthetic sequences.

Synthesis

  • Route1

    References

    • Letters in Organic Chemistry, , vol. 10, # 5 p. 348 - 352

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   67.06
  • LogP   -0.8159
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   0

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