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CS-W001157 4
Total: USD 88.00

N-Ethylcyclohexylamine

  • CAS No. 5459-93-8

  • Cat. No. CS-W016555
  • Purity≥96%
  • MDL No.MFCD00003834

*For research and further manufacturing use only, not for direct human use.

N-Ethylcyclohexylamine|CS-W016555

Structure of 5459-93-8

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General Information

  • CAS No. 5459-93-8
  • Cat. No. CS-W016555
  • Purity ≥96%
  • MDL No. MFCD00003834
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₇N
  • Molecular Weight 127.23
  • Synonym(s) n-ethyl-Cyclohexanamine; N-Ethylcyclohexylamine
  • SMILES C(NC1CCCCC1)C

Description

N-Ethylcyclohexylamine was used in the synthesis of a series of isatin-N-Mannich bases.

Application

N-Ethylcyclohexylamine serves as a versatile secondary amine building block in medicinal chemistry and process development. Its cyclohexyl scaffold provides favorable lipophilicity and metabolic stability, while the ethyl substitution enhances solubility and modulates basicity. The compound exhibits excellent bench stability, facilitates efficient functionalization in standard amine coupling reactions, and functions reliably in the synthesis of heterocyclic scaffolds and bioactive intermediates.

Synthesis

  • Route1
    • null|null
      103-84-4
    • ~91%
    • In-stock
      N-Ethylcyclohexylamine|CS-W016555
      5459-93-8

    References

    • Hirosawa, Chitaru; Wakasa, Noriko; Fuchikami, Takamasa Tetrahedron Letters, 1996 , vol. 37, # 37 p. 6749 - 6752
  • Route2
    • null|null
      108-91-8
    • null|null
      75-05-8
    • ~38%
    • In-stock
      N-Ethylcyclohexylamine|CS-W016555
      5459-93-8
    • In-stock
      N,N-Diethylcyclohexylamine|CS-0152031
      91-65-6

    References

    • Nacario, Ruel; Kotakonda, Shailaja; Fouchard, David M. D.; Tillekeratne, L. M. Viranga; Hudson, Richard A. Organic Letters, 2005 , vol. 7, # 3 p. 471 - 474
  • Route3
    • null|null
      103-84-4
    • ~36%
    • N-Cyclohexylacetamide|CS-0162808
      1124-53-4
    • In-stock
      N-Ethylcyclohexylamine|CS-W016555
      5459-93-8

    References

    • ChemCatChem, , vol. 5, # 10 p. 2843 - 2847

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS05,GHS06
Signal Word : Danger
UN#: 2734
Class : 8 (3)
Packing Group : Ⅱ
Hazard Statements : H226-H302+H332-H311-H314
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P301+P330+P331-P304+P340-P361-P363-P370+P378-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   1.9286
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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