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Structure of 5459-50-7
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2-Iodo-5-nitroaniline features a nitro group at the para position relative to the amino functionality, conferring strong electron-withdrawing character. The iodine substituent enables facile palladium-catalyzed cross-coupling reactions. This bench-stable, moisture-tolerant compound integrates readily into complex molecular architectures.
2-Iodo-5-nitroaniline serves as a versatile building block in the synthesis of functionalized heterocycles and pharmaceutical intermediates. The iodine group enables palladium-catalyzed cross-coupling reactions, while the nitro functionality supports sequential transformations including reduction to an amine or further electrophilic substitution. Its stability under standard bench conditions and compatibility with diverse reaction protocols make it a practical choice for multi-step synthetic sequences in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: